Thursday, March 27, 2014

Study shows what foods deposit fat and where it is deposited on your body


If you want to avoid developing an apple shape, then you should eat salmon and walnuts, new research suggests. Swedish researchers discovered that people who eat a lot of polyunsaturated fat gain more muscle - and less fat - than those who eat a lot of saturated fat. People who eat mainly polyunsaturated fat - which salmon and walnuts are rich in - also store less fat around their waists and their internal organs.
This was the first study on humans to show that the fat composition of food not only influences cholesterol levels in the blood and the risk of heart disease, but also where in the body fat will be stored. The findings have recently been published in the American journal Diabetes.

The study
Researchers at Uppsala University studied 39 young adult men and women of normal weight, who ate 750 extra calories a day for seven weeks. The goal was for them to gain 3% of their starting weight. The project received considerable attention when it started in 2011, partly because the extra calories were ingested in the form of muffins with high fat content, baked in the lab by Fredrik Rosqvist, a doctoral candidate and first author of the study.
One half of the subjects were random to eat surplus calories from polyunsaturated fat (sunflower oil), while the other half got their surplus calories from saturated fat (palm oil).  Both diets contained the same amount of sugar, carbohydrates, fat, and protein; the only difference between muffins was the type of fat. The increase in body fat and the distribution of fat in the body was measured using a magnetic resonance imaging (MRI scans) before and after the weight gain, as was the muscle mass in the body. Gene activity was measured in the abdominal visceral fat before and after the weight gain with the help of a gene chip that studies several thousand genes at a time.

The findings
Despite comparable weight gains between the two diet groups, the surplus consumption of saturated fat caused a markedly greater increase in the amount of fat in the liver and abdomen (especially the fat surrounding the internal organs, visceral fat) in comparison with the surplus consumption of polyunsaturated fat. Moreover the total amount of body fat was greater in the saturated fat group, while, on the other hand, the increase in muscle mass was three times less for those who ate saturated fat compared with those who ate polyunsaturated fat. The researchers believe their findings also suggest people who eat lots of polyunsaturated fat are less likely to develop heart disease and type 2 diabetes.

Bottom line
Thus, gaining weight on excess calories from polyunsaturated fat caused more gain in muscle mass, and less body fat than overeating a similar amount of saturated fat. Since most of us are in positive energy balance, and consequently gain weight slowly but gradually over time, the present results are highly relevant for most Western populations.
"Liver fat and visceral fat seems to contribute to a number of disturbances in metabolism. These findings can therefore be important for individuals with metabolic diseases such as diabetes. If the results regarding increased muscle mass following consumption of polyunsaturated fat can be confirmed in our coming studies, it will potentially be interesting for many elderly people, for whom maintaining muscle mass is of great importance in preventing morbidity", says Ulf Risérus, associate professor at the Department of Public Health and Caring Science and director of the study.

Not only how much fat your body has matters, but also WHERE the fat is stored
When it comes to the risk of developing diabetes and cardiovascular diseases, it seems more important where in the body the fat is stored than how much fat the body has. Visceral fat, along with a high proportion of fat in the liver, is closely associated with increased risk for developing type-2 diabetes. These fat depots are therefore important targets for new drugs and dietary strategies.
A number of studies have indicated that a higher intake of polyunsaturated fats from plant oils and nuts is associated with a decreased risk of type-2 diabetes, but the reasons for this remain unclear.
The present study proposes a potential explanation for such an association, showing that polyunsaturated fatty acids can affect fat distribution in the body more favorably than saturated fats, probably by regulating increased energy combustion or decreased storage of visceral fat in connection with calorie-rich diets.

Fat affects body's genes
The researchers were also able to see that over-consumption of saturated fats seems to be able to "turn on" certain genes in fatty tissue that increase the storage of fat in the abdomen and at the same time hamper insulin regulation. Polyunsaturated fats, instead, can "turn on" genes in visceral fat that in turn are linked to reduced storage of fat and improved sugar metabolism in the body.

The discovery may also be a contributing factor regarding the tendency of some individuals to accumulate fat in the liver and abdomen. The new findings suggest that the fat composition of the diet, in the long term, might play a role in preventing obesity-related disorders, like type-2 diabetes, at an early stage, before overweight develops.

"This is of great interest, as we lack preventive treatments for fatty liver and visceral fat today. The new findings also support international dietary recommendations, which, among other things, recommend replacing some saturated fat from meat, butter, and palm oil, for example, with unsaturated fats from plant oils and fatty fish", says Ulf Risérus.



Sources: http://www.eurekalert.org/, http://www.medicalnewstoday.com/, http://www.sciencedaily.com/, http://medicalxpress.com/, http://www.dailymail.co.uk/health